Post-Doctoral Training in the Center for Vascular Biology is available in individual laboratories within a multi-disciplinary and interactive environment with primary areas of interest in Vascular Biology, Angiogenesis, Signal Transduction, Proteomics, RNA Biology, Cell Biology. The ongoing research extends from endothelial lipid receptors, mechanisms of apoptotic cell engulfment in vascular lesions, developmental vascular biology, hypoxia-mediated control of angiogenic factor expression and the role of peptidases in pathological angiogenesis.

The fellows are funded through individual research and training grants. The focus is to foster Post-Doctoral career development through training in methodologies, research experimental design and interpretation, hypothesis development and testing, grant and manuscript writing, interaction with students and technical personnel in collaborative research, data and oral presentation skills. Fellows have easy access to a wide graduate and medical/dental school curriculum in the form of audit courses and superb research seminars ranging from Vascular Biology to other programs including Immunotherapy, Microbial Pathogenesis and Immunology, Neurobiology and Molecular Medicine. Post-Doctoral fellows are encouraged to present work in at least one national meeting per year and present at the internal Center for Vascular Biology seminar meetings held twice a month.

The center is housed in a state-of-the-art research building with excellent centralized core facilities for MS/MS protein sequencing, histology, flow cytometry and sorting, electron microscopy, microarray and a world-class imaging core (CBIT link).

Stipends are based upon years of experience and are modeled along the NIH guidelines. Full health insurance benefits are covered.

Faculty and Topics

• Timothy Hla, Ph.D., Director Role of EDG/S1P receptors in endothelial biology and lipid mediators modulated by COX-2 in breast cancer progression.
• Kevin Claffey, Ph.D. Mechanisms of hypoxia-induced VEGF expression via mRNA stability and role in tumor progression and angiogenesis.
• Ann Cowan, Ph.D. Advanced imaging applications to cell biology, computational cell biology tools and image reconstruction.
• Guo-Hua Fong, Ph.D. Role of VEGF receptors and hypoxia-mediated transcription factors in developmental vasculogenesis using genetic mouse models.
• Henry Furneaux, Ph.D. The regulation of gene expression by microRNAs.
• David Han, Ph.D Proteomic and bioinformatics approaches to vascular remodeling and apoptotic cell engulfment.
• Joel Pachter, Ph.D. The mechanisms by which leukocytes and pathogens invade the central nervous system.
• Linda Shapiro, Ph.D. Cell surface peptidases and their role in tumor and adaptive cardiac angiogenesis.
• Dan Wu, Ph.D. Investigation of the molecular basis and function of chemoattractant and Wnt-activated signaling networks using biochemical, cell and molecular biological, transgenic, functional genomic and proteomic approaches.